发表于2025-04-21
Bottle of Lies: The Inside Story of the Generic Drug Boom pdf epub mobi txt 电子书 下载
Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##这本书,或者说这篇报道揭露了印度仿制药企造假的前因后果及被揭露的过程。整本书的采证、叙事结构都可谓是深度报道的标杆。做到了内容充实,证据丰富,视角多元,层层递进,引人深思,余韵悠长。 非常适合国人阅读,之前热门的电影《我不是药神》为这本书奠定了一些基础,大家...
评分##一个这么好的题材,被作者写得稀烂。故事非常散乱且冗长。有种所有我调查到的内容都要填进去的杂乱感。人物脸谱化,凡正面角色一定要讲到成长经历,父亲职业的影响,反面角色一定是生活奢迷,草菅人命,毫无道德可言。350字装不下我的吐槽。可能需要写一篇长评。。。。。。
评分 评分##这本书像一个加长版bad blood 都是从上到下做假 不在意生产过程 该work的行业标杆FDA水土不服监管失灵 whistle blower心惊胆战地揭秘但是调查迟缓 可以感受到对global south的凝视 印象最深刻的是对whistle blower的比喻:大家都听说过可是没有人见过他们 说起仿制药的话题,相信绝大多数朋友第一时间想到的都是那部现象级的电影《我不是药神》的描写:效果和正牌药一模一样,往往都在印度那边生产,因为相关法律问题国内很难弄到…… 不过我对仿制药的印象却和那部电影不太一样,因为我的亲叔叔就患有慢粒细胞白血病,需要服用影片...
评分 评分 评分##药店卖高价来研发药,不义者用仿制药赚钱,悲悯者用仿制药救人,穷人用仿制药来活命。现如今,仿制药己不能单纯用好或坏来形容,而是一个包含了不同人不同愿望的大锅,我只希望都多一份宽容,药店让穷人活命,富人帮药店筹款,不义者受制裁,穷人尽力帮药店……希望一切都变好...
评分##仿制药“应该”是同等疗效、价格低廉的替代品,但诚如书中所说的严重违规、为了利益藐视生命的行为一定存在。而这些行为不是仿制药独有的,品牌药药企同样也有不公布所有临床试验数据、不提交严重不良反应事件等等违规害命的行为。最后受伤的总是患者。不管是仿制药还是品牌药...
评分##在这本书之前,我对仿制药的了解可以用两句话讲完:理想很丰满,现实很骨感。 一方面,我理解为什么我们需要仿制药。广大穷人(包括我自己)都渴望推动仿制药的出现——因为救命的原研药实在太贵了,尤其是在美国医疗市场的环境中。 另一方面,我也明白为什么在医保改革之后,...
Bottle of Lies: The Inside Story of the Generic Drug Boom pdf epub mobi txt 电子书 下载